rHGH is a Human Growth Hormone therapy that is
Clinically Proven: Safe, Effective and Pure.
rHGH is effective for:
Decreased body fat
Increase in lean muscle mass
Increased libido and energy
Relief of headaches and anxiety
Improved quality of sleep
Reduction in blood pressure
Improved physical appearance.
Homeopathic Human Growth Hormone for Physiologic
and Psychologic Health
Double-blind, placebo controlled study as published in Volume 5, Number
6, December 1999 issue of "Alternative & Complementary Therapies"
involving 87 subjects, ages 29-72 years old
Three Double-Blind Placebo-Controlled Studies
Barbara Brewitt, Ph.D., James Hughes, M.D.,
Elizabeth A. Welsh, Ph.D., Robert Jackson, D.C.
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Human growth hormone (hGH) receives a good deal of public attention
for the ability to build lean body mass, increase physical performance,
enhance immune function, and improve body composition and shape. Lean
body mass includes muscle, bone, and organ density, i.e., the body's
fat-free mass. Maintenance of lean body mass extends life, because muscle
weakness, organ failure, and death are direct results of lost lean body
mass. In one study, men, ages 61-80 years old, who injected pharmacologic
concentrations of 50 mg of recombinant hGH 3 times per week for 6 months
improved in health achieving a state that is more similar to a youthful
state by raising lean body mass by 8 percent, decreasing fat by 14 percent,
increasing spleen and liver sizes by 18 percent, and increasing bone
density. Other clinical studies on adults with growth-hormone deficiency
(GHD) found that hGH replacement therapy improved subjects' body composition
and quality of life.
Problems Associated with
Too Much or Too Little hGH
The American Association of Clinical Endocrinology defines GHD as a
cluster of self-perceived symptoms as listed in Table 1. Age-related
declines in hGH and insulin-like growth factor (IGF)-1 levels are also
used to define GHD. Following puberty, hGH declines exponentially. Growth-hormone
(GH) secretion peaks at 31 years of age, then declines by 14-50 percent
per dectension. In acromegaly, the most striking problems are enlargement
of the heart, lungs, liver, thymus, and spleen. Hyperthyroidism may
result in addition to hyperglycemia and glucosuria. Finally, overgrowth
of the bones in the face, hands, and feet occur. The jaw protrudes and
becomes massive, with thick lips and an overly large tongue, and there
is accentuation of the orbital and frontal ridges. The adrenal, thyroid,
and parathyroid glands hypertrophy or overgrow.
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Discussion
Chewable tablets of homeopathic recombinant human growth hormone
promoted significant physical, physiologic, and self-perceived
quality-of-life benefits compared to placebo in healthy adults,
ages 18-72 years old. Statistically significant were weight loss,
decreased hip size and increased upper-arm size compared to placebo
after 21 days of HhGH. Decreased hip size corresponds directly
to less fat storage. Injectable pharmacologic hGH at concentrations
of 0.125 international units(IU)/kg per week and 0.250 IU/kg per
week reduced hip size statistically after 6 months. The weight
loss measured in Boulder was consistent with increased lean body
mass. Clinical studies on GHD subjects who had injected pharmacologic
concentrations of hGH for 6 months showed no marked changes in
body weight. 6C + 100C + 200C HhGH evoked statistically significant
treatment and time effects and 6X + 12C HhGH evoked statistically
significant changes that were sensitive to gender, age, and baseline
parameters. Specifically, males responded better to 6X + 12C HhGH
in increasing upper-arm size, decreasing hip size, decreasing
fat, and increasing lean body mass. The greatest weight loss occurred
in participants who were using 6X + 12C HhGH. Reproducible increases
of more than 2 lbs in lean body mass occurred in subjects using
the 6C + 100C + 200C HhGH for 21 days compared to placebo. Chest
size in men increased significantly in 21 days on 6X + 12C HhGH
versus 6C + 100C + 200C HhGH. Human GH stimulates lipolysis in
adipose tissue directly. The findings in this HhGH study are consistent
with hGH's effect on fuel redistribution via the preferential
utilization of fat over glucose. A given subject's upper-arm size
at the end of the study was influenced by baseline age and arm
size, i.e., the younger the person, the greater were the increases
in upper-arm size at the end of the study. Clinical studies with
injectable GH demonstrated that the dosing schedule for people
who are more than 60 years old is considerably less than that
required with younger people. It may also be important that different
HhGH concentrations be provided to different age groups.
Uneven, random distribution of men and women into the different
groups may have affected the statistical significance of treatment
compared to placebo. In Boulder, the subjects in placebo group
were younger by an average of 2 years than the people in treatment
group. There was a statistically significant response effect related
to each subject's age, gender, and baseline values with 6X +12
C HhGH. Entry-level lean body mass had a proportionate effect
on how much lean body mass could be gained. Thus, the health status
of a person upon entering the study was statistically significant
on his or her ability to respond to HhGH. Two treatment effects
of HhGH that were not significantly influenced by baseline status
were body weight and hip size.
Age-related declines in normal serum IGF-1 levels have been reported.
We also observed age-related and time-related responsiveness to
HhGH in terms of changes in serum IGF-1 levels. Subjects in the
Seattle and Boulder studies between 32-57 years old responded
rapidly to treatment. Within the first 21 days of HhGH therapy,
IGF-1 levels rose 18±5 percent in Seattle and 21±13
percent in Boulder, while younger subjects required longer treatment
periods to achieve similar levels. A clinical study on healthy
elderly subjects 78 ± 2.5 years old injecting 0.03 mg/kg
per week had peak increases in serum IGF-1 levels in the first
month of 9 ± 3 percent. Because of the age- and time-related
variables, further study with larger sample sizes of subjects
clustered into specific age, gender-, and time-matched groups
may be necessary to show statistical significance.
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Conclusion
There were three major findings from these different double-blind placebo
controlled studies.
Homeopathic hGH
Produced Physiologic Effects
The first finding was that oral administration of HhGH produced physiologic
effects. Rises in serum IGF-1 levels occurred with both 6C + 100C +
200C HhGH and 6X + 12C HhGH compared to transient rises and final downward
trends in subjects who were on placebo. It is important to note that
6X + 12C HhGH stimulated a rapid 18 ± 10 percent physiologic
rise in serum IGF-1 level after only 7 days in Santa Fe subjects who
were not aware of what substance was being tested. These three studies
are the first double blind placebo-controlled studies to demonstrate
differences in the bloodstreams of healthy people in response to HhGH.
There have been several double-blind placebo-controlled studies that
used a combination of four homeopathic growth factors on people infected
with human immunodeficiency virus (HIV) that demonstrated measurable
increases in peripheral blood lymphocyte counts and decreases in viral
load.(36-39) Although homeopathy's molecular mechanism of action remains
to be fully elucidated, HhGH clearly evokes quantifiable physiologic
changes in the bloodstream.
Multiple Beneficial
Effects of Treatment Were Demonstrated
The second significant finding from these studies is that pharmacological
benefits of injectable hormonal replacement were experienced with a
homeopathic oral chewable tablet. Injectable growth hormone is well
known for its positive effects on lean body mass, producing weight and
fat loss, improving pulmonary function, lowering blood pressure, relieving
fatigue, improving vision, producing body shape changes, and improving
psychologic well-being, skin quality, sleep quality, and libido among
other benefits.
Similar to injectable hGH, chewable tablets of HhGH had positive effects
on lean body mass, produced weight and fat loss, relieved fatigue, produced
body shape changes, and improved psychologic well-being.
Homeopathic hGH also improved self-perceived measures related to quality
of life significantly, such as energy increase, weight loss, improved
vision, increased libido, improved sleep quality, improved breathing,
and improved skin softness. Thus, an oral formulation that was at least
4,000 times lower in concentration than an injectable hGH provided some
of the same benefits of the injectable hGH without its side effects.
Oral administration of HhGH lowered systolic blood pressure after 3
and 6 weeks, depending upon the formula that was used. Injectable hGH
at 700 µg per day, 3 times per week, for 6 months, corrected systolic
heart function that was caused by left-ventricle low-mass index.(40)
The degree of change in systolic function induced by HhGH requires further
and more extensive clinical study.
It is noteworthy that subjects who enrolled in this
study reported unique self-perceived benefits, far above the placebo
effect and never-before associated with hGH injections. For example,
subjects reported relief from bleeding gums, less phlegm build-up,
relief from coughing, relief from anger, relief from apathy, and
relief from urogenital discharges. These unique characteristics
derived from HhGH underlie the possibility that a different signaling
pathway is utilized than the pathway commonly outlined by molecular
biologists. In this way, HhGH is a different type of medicine
than injectable hGH. It is conceivable that the serial dilution
and shaking methods used to prepare homeopathic medicines contribute
to significant alterations in the physical and chemical properties
of the solvent and evoke bioelectric field signals to users. The
current double-blind placebo-controlled study represents a clinical
demonstration of Hahnemann's Law of Similars, i.e. positive actions
of hGH can be gained with a homeopathic formulation. Conventional
clinical practitioners administer pharmacologic concentrations
of injectable hGH for 3-4 weeks until optimal physiologic responses
are achieved and then they cycle the dose to every 3-4 days at
lower concentrations with periods of no treatment. The same dosing
schedule of 3-4 weeks with daily HhGH followed with cycling the
dose to every 3-4 days may be ideal for achieving optimal quality-of-life
benefits without negative effects. Additional and long term studies
are necessary to determine if side-effects above placebo effects
occur with HhGH. In our studies, no toxic side effects were reported.
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